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KMID : 1130320180610110371
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Korean Journal of Pediatrics
2018 Volume.61 No. 11 p.371 ~ p.373
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Scabies mimicking graft versus host disease in a hematopoietic cell transplant recipient
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Kim Dong-Sub
Choi Soo-Han
Lee Dong-Youn
Kim Ju-Youn
Cho Eun-Joo
Yoo Keon-Hee
Koo Hong-Hoe
Kim Yae-Jean
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Abstract
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Scabies is a highly contagious skin infestation caused by the mite, Sarcoptes scabiei var. hominis. Complex responses to scabies mites in the innate, humoral, and cellular immune systems can cause skin inflammation and pruritus. Diagnosis can be challenging because scabies resembles other common skin conditions. We report the first Korean case of scabies in a hematopoietic cell transplant (HCT) recipient, initially suspected of skin graft versus host disease (GVHD). A T-cell acute lymphocytic leukemia patient underwent a sibling-matched allogeneic HCT and developed pruritus after cell engraftment. Treatment for GVHD did not improve the symptoms. He was diagnosed with scabies 30 days after the onset of symptoms.
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KEYWORD
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Scabies, Graft versus host disease, Hematopoietic cell transplant
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